Method and apparatus to control sample carryover in analytical instruments

A measurement cell comprising:

• a top plate comprising a bottom planar surface;
• a manifold comprising
• a top manifold surface,
• a first o-ring groove in the top manifold surface comprising
• a first o-ring groove inner wall,
• a first o-ring groove outer wall, and
• a first o-ring groove bottom surface,
• a second o-ring groove in the top manifold surface and located radially outward from the first o-ring groove,
• a sample containing region within the circumference of the first o-ring groove, wherein the sample containing region comprises a sample containing region inlet at the bottom of the sample containing region and a sample containing region outlet at the top of the sample containing region, and
• a seal wash port between the first o-ring groove and the second o-ring groove, wherein the seal wash port comprises a seal wash port inlet at the bottom of the seal wash port and a seal wash port outlet at the top of the seal wash port;
• a first o-ring seated in the first o-ring groove and in contact with the bottom planar surface and in contact with the first o-ring groove bottom surface;
• a second o-ring seated in the second o-ring groove;
• wherein the first o-ring, the bottom planar surface, the top manifold surface, and the sample containing region outlet define a sample overflow region;
• wherein the sample containing region is configured to receive a fluid sample through the sample containing region inlet and is configured to flow the fluid sample through the sample containing region outlet into the sample overflow region, such that the fluid sample exerts pressure on the first o-ring such that the first o-ring impinges on the first o-ring groove outer wall, thereby allowing the fluid sample to enter a dead volume defined by the first o-ring, the bottom planar surface, the first o-ring groove inner wall, and the first o-ring groove bottom surface;
• wherein the first o-ring, the second o-ring, the bottom planar surface, the top manifold surface, and the seal wash port outlet define a seal wash region;
• wherein the seal wash port is configured to receive a fluid through the seal wash port inlet and is configured to flow the fluid through the seal wash port outlet into the seal wash region, such that the fluid exerts pressure on the first o-ring such that the first o-ring impinges on the first o-ring groove inner wall, thereby expelling the fluid sample from the dead volume.