Leads for implantable medical device that affects pressures within the intrathoracic cavity through diaphragmatic stimulation

A lead configured for implant on a surface of a biological membrane forming part of a hermetically sealed biological cavity, the lead comprising:

• a sensor assembly at a distal end of the lead, and comprising:
• a housing having a first end surface and a second end surface opposite the first end surface;
• a sensor structure associated with the first end surface, and comprising at least one sensor;
• and
• at least one fixation structure comprising a projecting structure in the form of a helix that extends away from the first end surface of the housing, and configured to preserve the hermetic integrity of the biological cavity after implant of the lead;
• a connector at a proximal end of the lead, and comprising at least one conductor pin;
• and
• a lead body extending between the sensor assembly and the connector, and comprising at least one conductor that electrically couples the at least one sensor to the at least one conductor pin,
• wherein the projecting structure comprises a middle section between a proximal section and a distal section, wherein a wire forming the middle section has a diameter that is less than the diameter of a wire forming the proximal section and a wire forming the distal section.

A lead configured for implant on a surface of a biological membrane forming part of a hermetically sealed biological cavity, the lead comprising:

• a sensor assembly at a distal end of the lead, and comprising:
• a housing having a first end surface and a second end surface opposite the first end surface;
• a sensor structure associated with the first end surface, and comprising a ring having a circumference and one or more electrodes and one or more motion sensors located on the ring and spaced apart around the circumference;
• and
• at least one fixation structure comprising a projecting structure configured to extend through the biological membrane, and an extension member surrounding the projecting structure and configured to form a hermetic seal with the surface of the biological membrane, which formed seal surrounds an area where the projecting structure extends through the biological membrane to thereby preserve the hermetic integrity of the biological cavity;
• a connector at a proximal end of the lead, and comprising a plurality of conductor pins;
• and
• a lead body extending between the sensor assembly and the connector, and comprising a plurality of conductors that electrically couple the one or more electrodes and the one or more motion sensors to the plurality of conductor pins.