Method and means to improve the effects of electrical cell and neuron stimulation with random stimulation in both location and time

An electrical stimulation apparatus for applying therapeutic neuromodulation by adjusting the location of an electrical stimulation caused by an electrical stimulator configured to be implanted in an animal comprising:

• providing a supporting structure configured to be attached to the animal,
• providing an electrode supporting structure with a proximal extremity, a distal extremity, a surface and an inner volume;
• providing a plurality of pads or electrodes at the surface of the electrode supporting structure,
• providing one or more electronic controlling unit which is configured to change the state of some of the electrodes from on to off and/or from off to on at different times or to leave the state of some of the electrodes unchanged,
• providing electrically connecting means connecting the electrodes at the surface of the electrode supporting structure to the one or more electronic controlling unit wherein,
• the one or more electronic controlling unit is configured for providing a change in the electrodes that are turned on providing electrical stimulation,
• wherein the locus of the electrical stimulation occurred at precise locations along the electrode supporting structure wherein it is possible to apply the electrical stimulation at a precise depth and at a precise angular orientation with respect to the targed tissue,
• wherein the electrical stimulation locus transition from either a single electrode or a combination of electrodes to either a different electrode or combination of electrodes in a pre-determined pattern.