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US 10,369,344 B2Granted
Apparatus and method to convey a fluid
AssigneeBiocompatibles UK Limited
InventorsThomas J. Simpson, Jim Hagerman
Life of this patent
Estimating the term…
Abstract
An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling. A method includes introducing a fluid including one or more microparticles into a fluid conduit including a coupling, aligning the fluid conduit near the coupling with a force field, and introducing the fluid includes delivering the one or more microparticles to a vasculature.
Claims8
A method comprising:
- introducing a fluid including one or more microparticles into a fluid conduit including a coupling and a nozzle to establish a fluid path through the fluid conduit and move the fluid through a stagnant region positioned radially outward of the nozzle, the nozzle including an input port at an upstream end thereof and an output port located in the fluid path at a distal-most downstream end thereof defining a central fluid path through the nozzle from the input port to the output port, the input port of the nozzle having a larger cross sectional area than the output port of the nozzle, and wherein the nozzle comprises one or more side ports positioned near the input port of the nozzle to provide at least one additional fluid path, wherein the fluid flows into the nozzle via the input port, a first portion of the fluid that flows into the nozzle via the input port flows through the central fluid path and out of the nozzle via the output port and into the fluid path, and a second portion of the fluid that flows into the nozzle via the input port flows through the one or more side ports and moves through the stagnant region and into the fluid path while bypassing the central fluid path of the nozzle;
- aligning the fluid conduit in a region near the coupling with a force field;
- and
- delivering the one or more microparticles to a vasculature.
1 more element
A method comprising:
- coupling a source of high density microparticles having high specific activity and a fluid conduit with a coupling and a nozzle to establish a fluid path through the fluid conduit and move a fluid through a stagnant region positioned radially outward of the nozzle;
- the nozzle including an input port at an upstream end thereof and an output port located in the fluid path at a distal-most downstream end thereof defining a central fluid path through the nozzle from the input port to the output port, the input port of the nozzle having a larger cross sectional area than the output port of the nozzle, and wherein the nozzle comprises one or more side ports positioned near the input port of the nozzle to provide at least one additional fluid path, wherein the fluid flows into the nozzle via the input port, a first portion of the fluid that flows into the nozzle via the input port flows through the central fluid path and out of the nozzle via the output port and into the fluid path, and a second portion of the fluid that flows into the nozzle via the input port flows through the one or more side ports and moves through the stagnant region and into the fluid path while bypassing the central fluid path of the nozzle;
- aligning the fluid conduit in a region near the coupling with a force field;
- and
- delivering the high density microparticles having the high specific activity to a mammal at a pressure of between about 5 psig and about 30 psig at the source.
2 more elements
A method comprising:
- introducing a fluid including one or more microparticles into a fluid conduit, the fluid conduit including a coupling and a nozzle;
- establishing a fluid path through the fluid conduit to move the fluid through a stagnant region positioned radially outward of the nozzle, the nozzle having a longitudinal axis and including an input port at an upstream end thereof and an output port located in the fluid path at a distal-most downstream end thereof defining a central fluid path through the nozzle from the input port to the output port, wherein at least a portion of the input port and at least a portion of the output port are in-line with the longitudinal axis of the nozzle, and wherein the nozzle comprises one or more side ports positioned near the input port of the nozzle to provide at least one additional fluid path, wherein the fluid flows into the nozzle via the input port, a first portion of the fluid that flows into the nozzle via the input port flows through the central fluid path and out of the nozzle via the output port and into the fluid path, and a second portion of the fluid that flows into the nozzle via the input port flows through the one or more side ports and moves through the stagnant region and into the fluid path while bypassing the central fluid path of the nozzle;
- aligning the fluid conduit in a region near the coupling with a force field;
- and
- delivering the one or more microparticles to a vasculature.
2 more elements
Dependencies are inferred from the claim text.