Dispenser

An enclosed aerosol source combination comprising an assembled combination of the aerosol source, a body and an enclosure:

• the aerosol source having:
• a canister,
• a spout at one end of the canister, the spout being movable inwards of the canister for substance release,
• a spring urging the spout outwards of the canister with a force required to be overcome for release movement inwards, and
• a valve for releasing a substance from the canister on longitudinal movement of the spout against the spring;
• the body having:
• a mouthpiece for inhalation/insufflation of the substance;
• a moveable junction member for receiving the spout;
• and
• a dispense mechanism able to be cocked to move the junction member and receive a substance dose and to be triggered by inhalation releasing the substance dose;
• the enclosure having:
• at least one dispense-mechanism positioning feature at a determined position;
• and
• a location member for the canister, the location member configured to be adjusted to provide a determined dose of the spout with respect to the at least one dispense-mechanism positioning feature after the aerosol canister has been assembled into the enclosure,
• an arrangement of the assembled combination being such that on movement of the spout through determined stroke with respect to the dispense-mechanism, positioning feature and against the spring substance release is predictable.