Sterile fluid pathway connection to drug containers for drug delivery pumps

A fluid pathway connection comprising:

• a drug container including
• a barrel having a proximal end and a distal end,
• a pierceable seal disposed at the proximal end of the barrel, and
• a cap disposed at the proximal end of the barrel;
• a piercing member;
• a fluid conduit;
• a connection hub, the piercing member being connected to the connection hub;
• and
• a sterile sleeve, one end of the sterile sleeve being fixedly coupled to the connection hub and an opposing end of the sterile sleeve being fixedly coupled to a proximal end of the drug container, the sterile sleeve being a pre-formed aspect of the pierceable seal, the piercing member being disposed within the sterile sleeve between the connection hub and the pierceable seal of the drug container in an initial unactivated position,
• wherein the pierceable seal and the connection hub are adapted for relative movement between the initial unactivated position wherein the piercing member does not pierce the pierceable seal, and an activated position wherein the piercing member extends through the pierceable seal, the sterile sleeve being compressible or collapsible and adapted to compress or collapse as the connection hub and the pierceable seal are moved relatively between the initial unactivated position and the activated position.

A drug delivery pump with integrated sterility maintenance features comprising:

• a fluid pathway connection including:
• a drug container including:
• a barrel having a proximal end and a distal end,
• a pierceable seal disposed at the proximal end of the barrel, and
• a cap disposed at the proximal end of the barrel;
• a piercing member;
• a fluid conduit;
• a connection hub, the piercing member being connected to the connection hub;
• and
• a sterile sleeve, one end of the sterile sleeve being fixedly coupled to the connection hub and an opposing end of the sterile sleeve being fixedly coupled to a proximal end of the drug container, the piercing member being disposed within the sterile sleeve between the connection hub and the pierceable seal of the drug container in an initial unactivated position,
• wherein the pierceable seal and the connection hub are adapted for relative movement between the initial unactivated position wherein the piercing member does not pierce the pierceable seal, and an activated position wherein the piercing member extends through the pierceable seal, the sterile sleeve being compressible or collapsible and adapted to compress or collapse as the connection hub and the pierceable seal are moved relatively between the initial unactivated position and the activated position;
• a housing;
• an assembly platform;
• an activation mechanism disposed on the assembly platform;
• an insertion mechanism disposed on the assembly platform;
• a power and control system disposed on the assembly platform;
• and
• a drive mechanism disposed on the assembly platform, the drive mechanism initially coupled to the drug container or adapted to be coupled to the drug container.