Methods and compositions for affecting immunological responsiveness
AssigneeCellPrint IP Holding, LLC
InventorDavid R. Kaplan
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Abstract
A method of treating a subject having a deficient immune response is described. The method includes administering a therapeutically effective amount of non-immune drug, or an analog or metabolite thereof, known to induce one or more autoimmune syndromes to the subject. Drugs known to induce one or more autoimmune syndromes, such as lupus-like syndromes, include immune checkpoint inhibitor blockers. Methods of identifying drugs capable of enhancing immunity are also described.
Claims14
A method of enhancing the immune responsiveness of a subject having a deficient immune response, comprising administering to the subject a therapeutically effective amount of a drug known to induce one or more autoimmune syndromes, or an analog thereof, which is also known to induce one or more autoimmune syndromes.
Dependencies are inferred from the claim text.