Treatment of mammalian physiological reaction of IgE antibodies present in said mammal upon contact with the corresponding antigen
OwnerIra Sandersinventor
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Abstract
A method is disclosed for blocking or reducing a physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a neurotoxin (CnT) derived from Clostridia sp.
Claims9
A method of treating an allergic condition or a symptom thereof in a patient in need thereof, comprising administering an effective amount of a neurotoxin (CnT) to a body structure involved in said allergic condition and/or a nerve and nerve ganglia supplying the body structure of the patient, wherein the CnT is isolated or purified from a species of Clostridia selected from the group consisting of C. botulinum, C. burtyricum and C. beratti, and wherein the allergic condition is selected from the group consisting of allergic rhinitis, allergic asthma, allergic gastroenteritis, allergic serous otitis media, allergic sinusitis, and allergic dermatitis.
Dependencies are inferred from the claim text.