Factor 1 protein, factor 2 protein and inhibitors thereof for use in treating or preventing diseases

A method of treating myocardial infarction in a subject, comprising:

• administering to the subject an effective amount of a pharmaceutical composition comprising a protein comprising the amino acid sequence according to SEQ ID NO:
• 1.

A method for treating a disease or disorder excluding myocardial infarction, comprising administering to a subject in need thereof an amount effective to treat the disease of a protein comprising the amino acid sequence according to SEQ ID NO:

• 1;
• wherein the disease or disorder is a heart-related disease selected from the group consisting of inherited cardiomyopathy, cardiomyopathy caused by spontaneous mutations, acquired cardiomyopathy, cardiomyopathy caused by infection of the myocardium, hypertensive heart disease caused by pulmonary arterial hypertension, arterial hypertension, diseases of the heart valves, ischemia reperfusion injury, inflammation, infection, trauma, mechanical overload, angina pectoris, and heart failure.