Coumarin derivatives and methods of use in treating hyperproliferative diseases

A method for treating polycystic kidney disease in a subject, comprising:

• administering to a subject an effective amount of a compound of the following formula:
• or a pharmaceutically acceptable salt or prodrug thereof, wherein:
• R1 is hydrogen, halogen, substituted or unsubstituted amino, or substituted or unsubstituted C1-6 alkyl;
• R2 is halogen, nitro, trifluoromethyl, substituted or unsubstituted amino, or substituted or unsubstituted C1-6 alkyl;
• and
• R5, R6, R7, R8, and R9 are each independently selected from hydrogen, halogen, substituted or unsubstituted alkoxy, trifluoromethyl, or substituted or unsubstituted C1-6 alkyl.