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US 10,369,132 B2Granted
Isoflavonoid compositions and methods for the treatment of cancer
AssigneeMEI Pharma, Inc.
InventorOfir Moreno
Life of this patent
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Abstract
Provided herein is a pharmaceutical composition comprising an isoflavonoid derivative and a cyclodextrin. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in cancer cells by administering such compositions. In specific instances, provided herein are intravenous compositions and therapies.
Claims15
A pharmaceutical composition consisting essentially of:
- i) d-cis-3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)-8-methylchroman-7-ol;
- ii) SBE7-β-CD;
- and
- iii) a liquid vehicle.
1 more element
A method of treating cancer in an individual in need of cancer therapy, the method comprising administering to the individual a composition consisting essentially of:
- i) d-cis-3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)-8-methylchroman-7-ol;
- ii) SBE7-β-CD;
- and
- iii) a liquid vehicle.
1 more element
A kit comprising a sealable, plastic infusion bag;
- and a composition consisting essentially of:
- i) d-cis-3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)-8-methylchroman-7-ol;
- ii) SBE7-β-CD;
- and
- iii) a liquid vehicle.
2 more elements
Dependencies are inferred from the claim text.