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US 10,369,125 B2Granted
Method of treating renal system damage
AssigneeUniversity of Utah Research Foundation
InventorTianxin Yang
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Abstract
Methods of treating the side effects of a toxic medical therapy using nitrated lipids are disclosed herein. In particular, the methods comprise the use of nitrated fatty acids or esters thereof to treat side effects, including organ system damage, caused by chemotherapy, radiotherapy, and the administration of other toxic agents.
Claims5
A method of treating renal system damage in a subject, comprising:
- administering to the subject an effective amount of a nitrated fatty acid,
- wherein the renal system damage is selected from the group consisting of distortion of the overall renal morphology, appearance of protein cast, oxidative stress, and apoptosis of organ cells;
- and
- wherein the nitrated fatty acid is 10-nitro oleic acid.
1 more element
Dependencies are inferred from the claim text.