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US 10,368,995 B2Granted
Methods for carbonate surface coating and related bone void filler compositions
AssigneeCaP Biomaterials, LLC
InventorLawrence A. Shimp
Life of this patent
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Abstract
Bone void filler compositions and methods for preparation to provide substrates with carbonate surface coatings to promote bone growth.
Claims17
A method of preparing discrete calcium carbonate particles on a substrate surface, said method comprising:
- providing a carbonatable calcium precursor component and applying said precursor component to a bone void filler substrate;
- and
- contacting said substrate with a carbon dioxide source in the presence of water to convert at least a portion of said applied carbonatable calcium precursor component to calcium carbonate and provide discrete calcium carbonate particles on said substrate.
A method of preparing a calcium carbonate surface coating, said method comprising:
- providing a carbonatable calcium precursor component selected from calcium chloride, calcium oxide and calcium acetate, and applying said precursor component to a bone void filler substrate;
- and
- contacting said substrate with a carbon dioxide source, optionally in the presence of water, to convert at least a portion of said applied carbonatable calcium precursor component to calcium carbonate and provide a coating of discrete, dispersed calcium carbonate particles on said substrate.
Dependencies are inferred from the claim text.