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US 10,368,993 B2Granted
Shape-memory-actuated materials for accelerated healing of orthopedic injuries
AssigneeSyracuse University
InventorsJames Henderson, Patrick T. Mather
Life of this patent
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Abstract
A three component system for repairing critically sized bone defects having a first shape memory polymer (SMP) component formed as a scaffold that fills the defects, a second SMP component formed as a restricting sleeve that stabilizes and supports osseointegration and osteoconduction, and a third SMP component formed as a two-dimensional cell culture substrate for engineering periosteal grafts.
Claims6
A method of repairing a bone defect, comprising the steps of:
- positioning a porous foam scaffold comprised of a shape memory polymer configured for expansion in response to a stimulus within said bone defect, wherein said porous foam scaffold has a pore size of 200 to 500 micrometers and a porosity of 79 percent plus or minus five percent;
- applying a stimulus to said scaffold to cause said porous foam scaffold to expand into said bone defect.
Dependencies are inferred from the claim text.