Bone implants for the treatment of infection
AssigneeSilver Bullet Therapeutics, Inc.
InventorsHoudin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
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Abstract
Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
Claims14
An implantable screw for insertion into bone to treat or prevent infection, the implant having a deployed configuration in which at least one antimicrobial ion releasing arm extends from the implantable screw and an undeployed configuration in which the arm is not extended from the implantable screw, the implantable screw further comprising:
- an elongate body having a threaded screw region configured for securing into bone;
- a channel extending proximally to distally through the implantable screw, wherein the arm is configured to extend through the channel and out of the implantable screw in the deployed configuration, further wherein the arm comprises an antimicrobial ion reservoir;
- and
- a galvanic reactor metal on the implantable screw configured to be in electrical communication with the reservoir when the implantable screw is in the deployed configuration to galvanically drive release of antimicrobial ions.
An implantable screw for insertion into bone to treat or prevent infection, the implant having a deployed configuration in which at least one silver-releasing arm extends from the implantable screw and an undeployed configuration in which the arm is not extended from the implantable screw, the implantable screw further comprising:
- an elongate body having a threaded screw region configured for securing into bone;
- a channel extending through the implantable screw, wherein the arm is configured to extend through the channel and out of the implantable screw in the deployed configuration, further wherein the arm comprises a silver reservoir;
- and
- a galvanic reactor metal configured to be in electrical communication with the silver reservoir when the implantable screw is in the deployed configuration to galvanically drive release of silver, but not in electrical communication with the silver reservoir when the implantable screw is in the undeployed configuration.
Dependencies are inferred from the claim text.