3D motion correction using 3D deformable registration and patient respiratory signals

A computer program product for 3D motion correction for diffusion weighted imaging images, the computer program product comprising a non-transitory computer readable storage medium having program instructions embodied therewith, the program instructions executable by a processor to cause the processor to:

• acquire a series of image slices from a medical imaging device;
• bin the series of image slices into bins based on breathing state, each bin comprising a plurality of slice locations, and each bin corresponding to a different breathing state;
• identify, for each of one or more B-values, a dominating breathing state having the most image slices in the series of image slices, wherein each image slice of the dominating breathing state is acquired at a different slice location;
• identify, for each of the B-values, one or more non-dominating breathing states having less image slices in the series of image slices than the dominating breathing state;
• and
• register, for each of the B-values, all of the one or more non-dominating breathing states to the dominating breathing state.

A system for 3D motion correction for diffusion weighted imaging images, the system comprising:

• a medical imaging device comprising a physiological monitoring unit and an image data processor configured to:
• acquire a series of image slices from the medical imaging device;
• bin the series of image slices into bins based on breathing state, each bin comprising a plurality of slice locations, and each bin corresponding to a different breathing state;
• identify, for each of one or more B-values, a dominating breathing state having the most image slices in the series of image slices, wherein each image slice of the dominating breathing state is acquired at a different slice location;
• identify, for each of the B-values, one or more non-dominating breathing states having less image slices in the series of image slices than the dominating breathing state;
• and
• register, for each of the B-values, all of the one or more non-dominating breathing states to the dominating breathing state.