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US 10,310,099 B2Granted
Method and apparatus for resolving individual signals in detector output data
AssigneeSouthern Innovation International Pty Ltd
InventorsPaul Andrew Basil Scoullar, Robin John Evans
Life of this patent
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Abstract
A method and apparatus for resolving individual signals in detector output data by obtaining an impulse response characterizing a detector. The method further includes obtaining digitized detector output data in a form of a digital time series and making estimates of a signal temporal position of at least one signal present in the detector output data. The method further includes forming a mathematical model based on the digital time series and determining an amplitude of the at least one signal indicative of an event based on the mathematical model.
Claims22
A method of detecting a plurality of individual radiation particles emitted from or transmitted through a specimen and measuring and outputting an energy of each of the detected individual radiation particles, the method comprising the following steps implemented on computer based hardware incorporating a detector circuit and one or more processor circuits:
- receiving a flux of the individual radiation particles in the detector circuit;
- obtaining an impulse response function characterizing a form of a discrete non-overlapping signal pulse generated in the detector circuit from single ones of the individual radiation particles received at the detector circuit;
- generating, by the detector circuit, an output data signal comprising a plurality of signal pulses corresponding to the detected plurality of individual radiation particles, at least two of the plurality of signal pulses temporally overlapping;
- determining a filter based on the impulse response function, the filter adapted to detect the form of the discrete non-overlapping signal pulse;
- digitizing, by the one or more processor circuits, the detector circuit output data signal to form a digital time series indicative of the plurality of signal pulses;
- identifying individual signals representing corresponding detected individual radiation particles in the digital time series by:
- i) filtering the digital time series with the filter to form a filtered digital time series and ii) detecting a plurality of peaks in the filtered digital time series, each peak representing a corresponding detected individual radiation particle;
- making parameter estimates of one or more parameters of the individual signals, wherein the one or more parameters comprise a signal temporal position of each of the peaks;
- forming a mathematical model of the digital time series as an accumulation of modelled individual signals, each of the modelled individual signals determined based on the impulse response function positioned at each of the signal temporal positions and an amplitude of each of the individual signals;
- determining the amplitude of the individual signals based on matching said mathematical model with the digital time series;
- and
- outputting the determined amplitude of each of the at least one of the individual signals, the determined amplitude being the measured energy of substantially each of the corresponding detected individual radiation particles.
9 more elements
An apparatus for detecting a plurality of individual radiation particles emitted from or transmitted through a specimen and measuring and outputting an energy of each of the detected individual radiation particles, the apparatus comprising:
- a detector circuit configured to receive a flux of the individual radiation particles;
- a memory circuit configured to store an impulse response function;
- and
- a processor circuit configured to:
- obtain the impulse response function characterizing a form of a discrete non-overlapping signal pulse generated in the detector circuit from single ones of the individual radiation particles received at the detector circuit;
- receive, from the detector circuit, an output data signal comprising a plurality of signal pulses based on the received flux of the detected individual radiation particles, at least two of the plurality of signal pulses temporally overlapping;
- determine a filter based on the impulse response function, the filter adapted to detect the form of the discrete non-overlapping signal pulse;
- digitize the detector circuit output data to form a digital time series;
- identify individual signals representing corresponding detected individual radiation particles in the digital time series by:
- i) filtering the digital time series with the filter to form a filtered digital time series and ii) detecting a plurality of peaks in the filtered digital time series, each peak representing a corresponding detected individual radiation particles;
- make parameter estimates of one or more parameters of the individual signals, wherein the one or more parameters comprise a signal temporal position of each of the peaks;
- form a mathematical model of the digital time series as an accumulation of modelled individual signals, each of the modelled individual signals determined based on the impulse response function positioned at each of the signal temporal positions and an amplitude of each of the individual signals;
- determine the amplitude of each of the individual signals based on matching said mathematical model with the digital time series;
- and
- output the determined amplitude of each of the at least one of the individual signals, the determined amplitude being the measured substantially energy of each of the corresponding detected individual radiation particles.
12 more elements
A non-transitory computer readable medium containing computer instructions stored therein to detect a plurality of individual radiation particles emitted from or transmitted through a specimen and measure and output an energy of each of the detected individual radiation particles by causing a computer processor circuit to:
- obtain an impulse response function characterizing a form of a discrete non-overlapping signal pulse generated in a detector circuit from single ones of the individual radiation particles received at the detector circuit;
- receive, from the detector circuit, an output data signal comprising a plurality of signal pulses based on radiation flux of the detected individual radiation particles at the detector circuit, at least two of the plurality of signal pulses temporally overlapping;
- determine a filter based on the impulse response function, the filter adapted to detect the form of the discrete non-overlapping signal pulse;
- digitize the detector circuit output data particles to form a digital time series;
- identify individual signals representing corresponding detected individual radiation particles in the digital time series by:
- i) filtering the digital time series with the filter to form a filtered digital time series and ii) detecting a number of peaks in the filtered digital time series, each peak representing a corresponding detected individual radiation particles;
- make parameter estimates of one or more parameters of the individual signals, wherein the one or more parameters comprise a signal temporal position of each of the peaks;
- form a mathematical model of the digital time series as an accumulation of modelled individual signals, each of the modelled individual signals determined based on the impulse response function positioned at each of the signal temporal positions and an amplitude of each of the individual signals;
- determine the amplitude of each of the individual signals based on matching said mathematical model with the digital time series;
- and
- output the determined amplitude of each of the at least one of the individual signals, the determined amplitude being the measured energy of substantially each of the corresponding detected individual radiation particles.
8 more elements
An apparatus for detecting a plurality of individual radiation particles emitted from or transmitted through a specimen and measuring and outputting an energy of each of the detected individual radiation particles, the apparatus comprising:
- means for receiving a flux of the individual radiation particles;
- means for obtaining an impulse response function characterizing a form of a discrete non-overlapping signal pulse generated in the means for receiving the flux of the individual radiation particles from single ones of the individual radiation received at the means for receiving the flux of the individual radiation;
- means for generating an output data signal comprising a plurality of signal pulses based on the received flux of the detected individual radiation particles, at least two of the plurality of signal pulses temporally overlapping;
- means for determining a filter based on the impulse response function, the filter adapted to detect the form of the discrete non-overlapping signal pulse;
- means for digitizing the output data signal to form a digital time series;
- means for identifying individual signals representing corresponding detected individual radiation particles in the digital time series by:
- i) filtering the digital time series with the filter to form a filtered digital time series and ii) detecting a number of peaks in the filtered digital time series, each peak representing a corresponding detected individual radiation particles;
- means for making parameter estimates of one or more parameters of the individual signals, wherein the one or more parameters comprise a signal temporal positions of each of the peaks;
- means for forming a mathematical model of the digital time series as an accumulation of modelled individual signals, each of the modelled individual signals determined based on the impulse response function positioned at each of the signal temporal positions and an amplitude of each of the individual signals;
- means for determining the amplitude of each of the individual signals based on matching said mathematical model with the digital time series;
- and
- means for outputting the determined amplitude of each of the at least one of the individual signals, the determined amplitude being the measured energy of substantially each of the corresponding detected individual radiation particles.
9 more elements
Dependencies are inferred from the claim text.