Methods, systems, and compositions relating to MiRNA-146a

A method of treating a subject suffering from a neurological disease or injury with cells capable of producing miR-146a microRNA, the method comprising:

• providing a cell population capable of producing exosomes containing miR-146a;
• and
• administering to the subject in need thereof, the cell population capable of producing exosomes containing miR-146a microRNA in a pharmaceutically effective amount to treat the subject with respect to the neurological disease or injury.

A method of treating a subject suffering from dementia, brain injury, neuropathy, stroke or multiple sclerosis with exosomes containing miR-146a microRNA, the method comprising:

• administering to the subject in need thereof, the exosomes containing miR-146a microRNA in a pharmaceutically effective amount to treat the subject with the dementia, brain injury, neuropathy, stroke or multiple sclerosis.

A method of treating a subject suffering from stroke with exosomes containing miR-146a the method comprising:

• administering to the subject in need thereof, the exosomes in a pharmaceutically effective amount to treat the subject with the stroke.