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US 10,308,763 B2Granted
Aqueous polyglycidol synthesis with ultra-low branching
AssigneeVanderbilt University
InventorsEva M. Harth, Benjamin R. Spears
Life of this patent
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Abstract
Disclosed herein are glycidol-based polymers, nanoparticles, and methods related thereto useful for a variety of applications, including, but not limited to, drug delivery. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Claims19
A polymer comprising repeating units selected from
- and repeating units selected from
- wherein R0 is selected from H, alkyl, NH2, and R1;
- wherein R1 comprises a crosslinking functionality;
- wherein repeating units A1, A2, B1, and B2 account for at least about 50 wgt % of the polymer;
- wherein the ratio of (A1+A2):(B1+B2) is greater than 1;
- and
- wherein the polymer does not comprise a
- moiety;
- and
- wherein the polymer is crosslinked.
7 more elements
A polymer comprising repeating units selected from
- and repeating units selected from
- wherein R0 is selected from H, alkyl, NH2, and R1;
- wherein R1 comprises a crosslinking functionality;
- wherein repeating units A1, A2, B1, and B2 account for at least about 50 wgt % of the polymer;
- wherein the ratio of (A1+A2):(B1+B2) is greater than 1;
- and
- wherein the polymer does not comprise a
- moiety;
- and
- wherein repeating units A1, A2, B1 and B2 account for at least about 100 wgt% of the polymer.
7 more elements
A polymer comprising repeating units selected from
- and repeating units selected from
- wherein R0 is selected from H, alkyl, NH2, and R1;
- wherein R1 comprises a crosslinking functionality;
- wherein repeating units A1, A2, B1, and B2 account for at least about 50 wgt % of the polymer;
- wherein the ratio of (A1+A2):(B1+B2) is greater than 1;
- and
- wherein the polymer does not comprise a
- moiety;
- and
- wherein the polymer does not comprise a unit or repeating unit formed from diglycidyl ether.
7 more elements
A polymer comprising repeating units selected from
- and repeating units selected from
- wherein R0 is selected from H, alkyl, NH2, and R1;
- wherein R1 comprises a crosslinking functionality;
- wherein repeating units A1, A2, B1, and B2 account for at least about 50 wgt % of the polymer;
- wherein the ratio of (A1+A2):(B1+B2) is greater than 1;
- and
- wherein the polymer does not comprise a
- moiety, and
- wherein the polymer does not comprise an initiator other than glycidol.
6 more elements
Dependencies are inferred from the claim text.