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US 10,308,683 B2Granted
Bicyclic lipolantipeptide, preparation and use as antimicrobial agent
AssigneeDeinove
InventorsJosef Aszodi, Denis Carniato, Dominique Le Beller, Guillaume Lesquame, Marie-Helene Quernin
Life of this patent
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Abstract
The invention relates to a new bicyclic lipolantipeptide, representing a new class of lantipeptide, and salts thereof, their preparation from a culture of a Microbacterium arborescens, and their use as antimicrobial agent in the prevention and treatment of infections in humans, animals or plants.
Claims8
A bicyclic lipolantipeptide comprising (i) the amino acids Ala, Gln, Leu and Ser, each being of the L-configuration, and Gly;
- (ii) an aminovinylthio group;
- and (iii) a saturated or unsaturated linear fatty acid chain substituent, the terminal carbon of the fatty acid chain carrying a guanidine group optionally substituted by one or two (C1-C6) alkyl groups, and any acid salt thereof, wherein said bicyclic lipolantipeptide is selected from:
- or
- ( ) m and ( ) n representing a total of 7 CH2 groups.
1 more element
Dependencies are inferred from the claim text.