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US 10,308,636 B2Granted
Aromatic heterocyclic compound
AssigneeMitsubishi Tanabe Pharma Corporation
InventorsKunio Saruta, Norimitsu Hayashi, Osamu Sakurai, Hiroaki Sawamoto, Eri Ooboki
Life of this patent
Estimating the term…
Abstract
The compound represented by the general formula: wherein ring A is benzene which may be substituted and the like; ring B is benzene which may be substituted and the like; X is a single bond and the like; Y is alkyl which may be substituted and the like; Z is CR1 or nitrogen atom; R1 is hydrogen and the like; R2 is alkyl which may be substituted and the like or a pharmaceutically acceptable salt thereof is useful as a prevention/treatment agent of obesity, diabetes, and the like.
Claims4
A compound represented by the general formula (1-A):
- [wherein ring A is pyridine which may be substituted with 1 to 3 alkyl groups;
- ring B1 is benzene which may be substituted with 1 to 3 substituent groups which are each independently alkyl, halogen or cyano;
- R1 is hydrogen, halogen atom, alkoxy, or alkyl which may be substituted with 1 to 6 halogen atoms;
- R2a is the formula as below:
- {wherein Z′ represents a single bond, alkylene, -Alk-O—, or -Alk1-O-Alk2-, (wherein Alk, Alk1, and Alk2 each independently represent alkylene, and the bond at the right end represents a bond to ring C),
- ring C represents an aromatic hydrocarbon group,
- R3 and R4 each independently represent hydrogen, halogen atom, alkyl which may be substituted with 1 to 6 halogen atoms, or alkoxy which may be substituted with alkoxy or 1 to 6 halogens atoms};
- X is a single bond or —O—;
- Ya is alkyl which may be substituted with 1 to 3 substituent groups which are aminocarbonyl which may be substituted with alkyl which may be substituted with 1 to 3 hydroxy and carboxy, or cycloalkyl which may be substituted with 1 to 3 carboxyalkyl groups];
- or a pharmaceutically acceptable salt thereof.
7 more elements
Dependencies are inferred from the claim text.