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US 10,308,632 B2Granted
Antifungal compounds and processes for making
AssigneeVPS-3, Inc.
InventorsDavid Dale Wirth, Christopher M. Yates
Life of this patent
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Abstract
Provided are polymorphic forms of compound 5 or 5*, or mixtures thereof, and polymorph forms of compound 14 or 14*, or mixtures thereof. Also provided are methods of preparing compound 5 or 5*, or mixtures thereof, and methods of preparing compound of 14 or 14*, or mixtures thereof, which are useful as antifungal agents. In particular, provided is new methodology for preparing polymorphs of the compounds described and substituted derivatives thereof.
Claims3
A polymorph of a compound of formula 5,
- characterized by at least one of:
- (i) a powdered X-ray diffraction pattern having two or more peaks expressed in degrees 2-theta±0.2° and selected from peaks delineated in the pattern of FIG. 8;
- or
- (ii) a DSC thermogram showing an endotherm at about 65-85° C.
1 more element
Dependencies are inferred from the claim text.