Organoselenium compounds, method for producing same, and pharmaceutical uses thereof in particular as antitumor agents
AssigneeTetrahedron
InventorsJean-Claude Yadan, Irene Erdelmeier, Marc Moutet, Remi Lebel
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AssigneeTetrahedron
InventorsJean-Claude Yadan, Irene Erdelmeier, Marc Moutet, Remi Lebel
Estimating the term…
The invention relates to a selenium compound. Said selenium compound has formula (I), where R1=alkyl; R2=H, R4C(=0), R4OC(=0), a-aminoacyl, CH3SeCH2CH2CH(NH2)C(=0), CH3SeCH2CH2CH(OH)C(=0); X=OH, OR3, NH2, NR4R5, α-amino acid, CH3SeCH2CH2CH(COOH)NH—, CH3SeCH2CH2CH(COOH)0-; R3=alkyl; R4=alkyl, aryl; R5=H, alkyl, aryl; R4 and R5 which can together form a 5- or 6-membered cycloalkyl radical which can comprise a heteroatom; provided that when X=NH-terbutyl, R2≠C(=0)CH3. Said compound can be used as a pharmaceutical substance, in particular as an antitumour substance.
A selenium compound having the following general formula (I):
Dependencies are inferred from the claim text.