Back to results
US 10,308,596 B2Granted
HDAC8 inhibitors for treating cancer
AssigneesCity of Hope, Taipei Medical University, Academia Sinica
InventorsYa-Huei Kuo, Wei-Jan Huang, Chung-I Chang
Life of this patent
Estimating the term…
Abstract
Provided herein, inter alia, are compound and methods of treating cancer by inhibiting HDAC8.
Claims9
A compound having the formula (I):
- wherein:
- R1 is substituted or unsubstituted 2 to 20 membered heteroalkyl, substituted or unsubstituted C3-C7 cycloalkyl, substituted or unsubstituted 3 to 7 membered heterocycloalkyl, substituted or unsubstituted C3-C7 aryl, or substituted or unsubstituted 3 to 7 membered heteroaryl;
- and
- R2 is substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted 2 to 20 membered heteroalkyl, substituted or unsubstituted C3-C7 cycloalkyl, substituted or unsubstituted 3 to 7 membered heterocycloalkyl, substituted or unsubstituted C3-C7 aryl, or substituted or unsubstituted 3 to 7 membered heteroaryl.
1 more element
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.