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US 10,308,414 B2Granted
Method and system for calculating a suitability indicator
AssigneeBoehringer Ingelheim International GmbH
InventorEduard Balthes
Life of this patent
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Abstract
Methods and systems for calculating a suitability indicator which corresponds to a suitability of a packaging system for packaging a substance, where a stability indicator which corresponds to a stability of the substance or of a component of the substance is determined as a function of at least one ambient condition, preferably the relative humidity and/or temperature of the environment of the substance, and the suitability indicator is calculated with at least one parameter relating to the ambient condition and with the stability indicator of the substance.
Claims23
A method, comprising:
- computing by simulation a respective suitability indicator for each of a plurality of packaging systems, where each such packaging system is a candidate for packaging a substance, wherein each suitability indicator corresponds to a respective suitability of a respective one of the plurality of packaging systems to protect the substance under defined climatic ambient conditions, wherein the suitability indicator is computed based on:
- (i) a stability indicator, which corresponds to at least one of a physical and chemical stability of the substance, or of a component of the substance, and which is determined as a function of at least one ambient condition of the substance, and (ii) a permeation model, which includes:
- (a) sorption data of the substance or parameters corresponding thereto, (b) at least one of the sorption data of the package, permeation data of the package and the at least one parameter relating to the at least one ambient condition of the substance;
- and
- selecting one or more of the plurality of packaging systems based on the suitability indicator.
2 more elements
Dependencies are inferred from the claim text.