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US 10,307,496 B2Granted
Method for sterilization of aqueous polysaccharide solutions and sterile aqueous polysaccharide solutions
AssigneeHeraeus Medical GmbH
InventorsSebastian Vogt, Thomas Kluge
Life of this patent
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Abstract
Sterilization method according to which an aqueous polysaccharide solution is stored in the presence of a lactone and a buffer system for a period of at least 24 hours, and a sterile polysaccharide solution produced in this way.
Claims15
Method for sterilizing aqueous polysaccharide solutions, comprising:
- adding a β-lactone to an aqueous solution of a polysaccharide in the presence of a buffer, thereby forming a mixture;
- and
- storing the mixture at a temperature of 4° C. to 40° C. for a period of at least 24 hours, wherein the added β-lactone is present in the mixture in an amount greater than or equal to 0.5% by weight.
Dependencies are inferred from the claim text.