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US 10,307,479 B2Granted
Therapy-enhancing glucan
AssigneeSloan-Kettering Institute for Cancer Research
InventorNai-Kong V. Cheung
Life of this patent
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AssigneeSloan-Kettering Institute for Cancer Research
InventorNai-Kong V. Cheung
Estimating the term…
This invention provides a composition comprising an effective amount of glucan capable of enhancing efficacy of antibodies. This invention further provides the above compositions and a pharmaceutically acceptable carrier. This invention also provides a method for treating a subject with cancer comprising administrating the above-described composition to the subject. This invention provides a composition comprising effective amount of glucan capable of enhancing efficacy of vaccines. This invention also provides a method of treating a subject comprising administrating the above pharmaceutical composition to the subject. This invention provides a composition comprising effective amount of glucan capable of enhancing efficacy of natural antibodies. This invention provides a composition comprising effective amount of glucan capable of enhancing host immunity. This invention also provides a composition comprising effective amount of glucan capable of enhancing the action of an agent in preventing tissue rejection.
A method of enhancing the antitumor effect of an antibody in a subject suffering from cancer, comprising administering to said subject said antibody, and a β-(1,3)-glucan obtained from oat, wheat, or moss, in an amount effective to enhance the anti-tumor effect of said antibody, wherein said glucan alone has little or no effect on said cancer, and has a molecular weight from about 40,000 to about 359,000 Daltons.
Dependencies are inferred from the claim text.