Use of short synthetic peptide for the treatment and/or prophylaxis of dry eye disease
AssigneeMackay Memorial Hospital
InventorsTsung-Chuan Ho, Yeou-Ping Tsao
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Abstract
Disclosed herein are synthetic peptides and compositions comprising the same for the treatment and/or prophylaxis of an ocular disease, particularly, dry eye disease. Also disclosed herein are methods of treating and/or preventing an ocular disease by administering to a subject in need of such treatment a composition containing a synthetic peptide of the present disclosure.
Claims13
A synthetic peptide consisting of 7 consecutive amino acid residues set forth as DLYRX1X2S (SEQ ID NO:
- 1), wherein X1 and X2 are respectively leucine and arginine, valine and arginine, glutamine and arginine, or glutamine and lysine.
A method of treating a subject suffering from a dry eye disease (DED) comprising administering to the subject an effective amount of a synthetic peptide consisting of 7 consecutive amino acid residues set forth as DLYRX1X2S (SEQ ID NO:
- 1), wherein X1 and X2 are respectively leucine and arginine, valine and arginine, glutamine and arginine, or glutamine and lysine.
Dependencies are inferred from the claim text.