Azabenzimidazole derivatives as agonists of the AMP-activated protein kinase

A compound of formula

• wherein
• R1 is selected from the group consisting of F and Cl;
• X is selected from the group consisting of a divalent straight-chained or branched —C1-3-alkyl-O— linker attached via the O-atom to the imidazopyridine core and
• a trivalent linker selected from
• attached via the O-atom to the imidazopyridine core and attached via the remaining two binding positions to vicinal carbon atoms of group Y;
• and
• Y is phenyl,
• optionally substituted with 1 to 2 groups independently selected from F, Cl, NC—, H3C—, F3C—, and H3C—O—,
• but mandatorily substituted with a group selected from RSRS′(O═)S═N—, RSRS′(O═)S═N—C1-3-alkyl-, RSRS′(O═)S═N—C(═O)—, (RN)N═S(═O)(RS)—, (RN)N═S(═O)(RS)—CH2—, RSRS′(RN′—N═)S═N—C(═O)—, RSRS′(O═)S═N—C(═O)—C1-3-alkyl-, RSRS′(O═)S═N—C(═O)—C2-3-alkenyl-, and RSRS′(RN′—N═)S═N—,
• wherein RN is selected from H, NC— and C1-4-alkyl, and RN′ is selected from H and NC—,
• wherein RS is selected from H3C—, H5C2— and cyclopropyl, and RS′ is independently selected from C1-4-alkyl- and C3-6-cycloalkyl, from an aryl group selected from phenyl and benzyl, and from the heteroaryl group pyridinyl,
• wherein any alkyl and cycloalkyl group mentioned hereinbefore under RN, RS and RS′ is optionally substituted with F, (C1-3-alkyl)2N—, (C1-3-alkyl)HN—, H2N—, NC—, HO—, H3C—, and H3C—O—,
• wherein any aryl and heteroaryl group mentioned hereinbefore under RS′ is optionally substituted with 1 to 3 groups independently selected from halogen, NC—, HO—, C1-3-alkyl, and C1-3-alkyl-O—,
• wherein in any definition mentioned hereinbefore and if not specified otherwise, any alkyl group or sub-group may be straight-chained or branched,
• or a salt thereof.