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US 10,307,401 B2Granted
Compositions and methods for treatment of prostate cancer
AssigneeCalifornia Institute of Technology
InventorsPeter B. Dervan, Nickolas G. Nickols, Fei Yang, Alexis A. Kurmis
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Abstract
The present invention relates to compositions and methods for the treatment of prostate cancer. The present invention relates to polyamides and prostate agents, for example, to inhibit an androgen receptor signaling axis, and the use of these compositions in the treatment of prostate cancer.
Claims9
A combination drug that inhibits the growth of a prostate cancer cell, wherein the combination drug comprises a polyamide and a prostate agent, wherein the polyamide has structure 61 as follows:
- and wherein the prostate agent is enzalutamide.
Dependencies are inferred from the claim text.