Application of naringenin and naringin in tumor radiotherapy
AssigneesInstitute of Biophysics, Chinese Academy of Sciences, Topfond Pharmaceutical Co., Ltd.
InventorsWei Liang, Chun Ling Zhang, Wen Feng Zeng, Chao Zhang, Luo Yang Wang
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Abstract
The present invention provides applications of a small molecular flavonoid compound in preparing a medication for sensitizing/synergizing tumor radiation therapy as well as reducing radioactive damage. The small molecular flavonoid compound can be naringenin, hesperetin, luteolin and apigenin, etc. The medication contains a small molecular flavonoid compound and a plurality of conventional pharmaceutical additives; wherein the small molecular flavonoid compound is an active ingredient.
Claims10
A method of sensitizing tumor radiotherapy as well as reducing radiation-induced toxicity, comprising the steps of:
- (1) administering orally an effective amount of medication before an irradiation;
- (2) conducting the irradiation;
- (3) administering orally the effective amount of the medication after the irradiation;
- wherein the medication comprises a small molecular flavonoid compound selected from the group consisting of naringenin, hesperetin, luteolin and apigenin.
Dependencies are inferred from the claim text.