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US 10,307,380 B1Granted
Composition and method for transdermal lidocaine delivery
AssigneeProSolus, Inc.
InventorJuan A. Mantelle
Life of this patent
Estimating the term…
Abstract
Adhesive formulations are provides for manufacturing matrix-type lidocaine patches having improved performance, manufacturability and stability.
Claims11
A packaged matrix-type transdermal drug delivery system inside a sealed package, wherein:
- a) said transdermal drug delivery system comprises (1) an adhesive matrix layer comprising a lidocaine base in a polyisobutylene adhesive matrix, wherein the adhesive matrix layer comprises from about 3.0 to about 5.0 weight parts lidocaine base, from about 84.0 to about 94.0 weight parts polyisobutylene, and from about 3.0 to about 7.0 weight parts cross-linked homopolymer of N-vinyl-2-pyrrolidone, and (2) a non-woven fabric backing layer;
- and
- b) said sealed package comprises opposing layers of an acrylonitrile-methyl acrylate copolymer and foil liner.
Dependencies are inferred from the claim text.