US 10,307,361 B2 · Vesicles containing saccharide isomerate, hydrolyzed lupine protein, and intercorneocyte lipid mimetics as active ingredient, and composition for skin external application comprising the same

Abstract

The present invention relates to a vesicle containing a saccharide isomerate, a hydrolyzed lupine protein, and an intercorneocyte lipid mimetics as an active ingredient, and a composition for skin external application including the vesicle, and more particularly, to a vesicle including: an aqueous phase part including a saccharide isomerate and a hydrolyzed lupine protein; and an oil phase part including an intercorneocyte lipid mimetics, lysolecithin, and glycerin. The vesicle includes the intercorneocyte lipid mimetics together with the saccharide isomerate and the hydrolyzed lupine protein as contents, so that the vesicle is excellent in a skin barrier recovery function and a skin moisturizing effect upon skin application. In addition, the vesicle is excellent in phase stability, so that the vesicle is suitable to be commercialized as various compositions for skin external application.

Claims6

Dependent claims

A vesicle containing a saccharide isomerate, a hydrolyzed lupine protein, and an intercorneocyte lipid mimetics as an active ingredient, the vesicle comprising:

an oil phase part obtained by dispersing 10 wt % to 75 wt % of the intercorneocyte lipid mimetics and 1 wt % to 10 wt % of lysolecithin in 1 wt % to 20 wt % of glycerin;
and
an aqueous phase part obtained by dissolving 0.01 wt % to 7 wt % of the saccharide isomerate and 0.01 wt % to 7 wt % of the hydrolyzed lupine protein in the balance of purified water,
wherein the intercorneocyte lipid mimetics includes 10 wt % to 70 wt % of an intercorneocyte lipid component, 0.1 wt % to 20 wt % of an amphoteric surfactant, 2 wt % to 20 wt % of saturated lecithin, 5 wt % to 20 wt % of glycerin, and the balance of purified water based on a total weight of the intercorneocyte lipid mimetics.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

15/820,093Filed 21 Nov 2017

Priority

KR 10-2016-015540822 Nov 2016

Published

US 2018/0140528 A124 May 2018

Granted

4 Jun 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61K 8/645
Proteins; Peptides; Derivatives or degradation products thereof: proteins of vegetable origin; Derivatives or degradation products thereof
A61K 8/14
Characterised by special physical form: liposomes; Vesicles
A61K 8/345
Alcohols: containing more than one hydroxy group
A61K 8/361
Carboxylic acids; Salts or anhydrides thereof: carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof

Vesicles containing saccharide isomerate, hydrolyzed lupine protein, and intercorneocyte lipid mimetics as active ingredient, and composition for skin external application comprising the same

Life of this patent

Vesicles containing saccharide isomerate, hydrolyzed lupine protein, and intercorneocyte lipid mimetics as active ingredient, and composition for skin external application comprising the same

Life of this patent

Abstract

Claims6