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US 10,307,279 B2Granted
Ingestible delivery systems and methods
AssigneeAllurion Technologies, Inc.
InventorsJonathan Wecker, Shantanu K. Gaur, Bruce A. Horwitz, Samuel G. Levy
Life of this patent
Estimating the term…
Abstract
Methods, devices and systems for delivering a device assembly using a shaped body allowing for ease of ingestion of a gastric device into a gastric space, allowing the gastric device to expand to occupy volume within the gastric space and, after an effective period of time release from the body.
Claims20
An ingestible delivery system for ingestion of an object by a patient, the delivery system comprising:
- a dosage shape having the object embedded therein to facilitate delivery of the object into the gastric space of the patient, where the dosage shape extends away from the object with bi-lateral symmetry to prevent the patient from sensing the object during ingestion, the dosage shape having a length along a first axis between a proximal end and a distal end, where the length is greater than a width of the dosage shape, a first surface and a second surface disposed on opposing sides of a plane of bi-lateral symmetry, a thickness between the first surface and the second surface, the first and second surfaces being smoothly continuous between the proximal end and distal end;
- a bulge region on the first surface of the dosage shape, where the bulge region comprises a maximum thickness of the dosage shape;
- a proximal tapering surface on the first surface that tapers from the bulge region to the proximal end such that a proximal thickness of the dosage shape decreases along the first axis towards the proximal end;
- a distal tapering surface on the first surface that tapers from the bulge region to the distal end, such that a distal thickness of the dosage shape decreases along the first axis where a length of the proximal tapering surface is less than a length of the distal tapering surface;
- and
- where the dosage shape comprises a degradable material that is degradable in the gastric space allowing for release of the object subsequent to ingestion.
3 more elements
An ingestible delivery system for ingestion by a patient, the delivery system comprising:
- a dosage shape encasing an object for delivery into the gastric space of the patient, where the dosage shape comprises a top surface that tapers from a bulge region along both a first axis and a second axis to form an arch shape configured to substantially conform to a palatal arch of the patient, where a first region along the top surface distal from the bulge region comprises a length greater than a length of a second region that is proximal relative to the bulge region;
- the dosage shape comprising a bottom surface opposite to the top surface and having a shallow convex surface being smoothly continuous and extending along a length of the dosage shape, where the top surface and bottom surface combine to reduce a swallowing resistance by mimicking a large bolus of food as formed by a mouth of the patient just prior to initiating swallowing;
- and
- where the dosage shape comprises a degradable material that is degradable in the gastric space allowing for release of the object subsequent to ingestion, where the degradable material surrounds the object to prevent the patient from sensing the object during ingestion.
1 more element
Dependencies are inferred from the claim text.