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US 10,307,140 B2Granted
Device for detection of hepatocellar carcinoma (HCC) using an octanoate breath test
AssigneeExalenz Bioscience Ltd.
InventorsGil Guggenheim, Ilan Ben-Oren, Avraham Hershkowitz, Yaron Ilan
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Abstract
Methods and systems for diagnosis, prognosis and monitoring of hepatocellular carcinoma (HCC). Specifically, the present invention relates to the use of breath tests based on isotope-labeled octanoate in the detection and monitoring of HCC.
Claims16
A device for hepatocellular carcinoma (HCC) detection comprising a processor configured to:
- obtaining a level of an isotope-labeled octanoate metabolic product measured in a subject's exhaled breath with a sensor following administering the isotope-labeled octanoate;
- comparing the measured level of the isotope-labeled octanoate metabolic product to a reference level;
- and
- detecting HCC based on a difference between the measured level of the isotope-labeled octanoate metabolic product and the reference level;
- wherein a significantly decreased level of isotope-labeled octanoate metabolic product is indicative of active HCC.
2 more elements
Dependencies are inferred from the claim text.