ECG evaluation
AssigneeUniversity of Leicester
InventorsWilliam B. Nicolson, Andre G. Ng
Life of this patent
Estimating the term…
Abstract
A method for assessing the electrical function of a heart, a method for determining a subject's need for the implantation of an implantable cardioverter defibrillator or the need for administration of an anti-arrhythmic agent, and apparatus for assessing the function of the heart and a computer program product. The methods and products involve analysis of ECG.
Claims23
A method for assessing the electrical function of a heart, the method comprising the steps of:
- providing an ECG, the ECG having a plurality of leads;
- determining, for each lead of the plurality of leads, at more than one time point, an output value corresponding to an action potential duration;
- determining, for each lead of the plurality of leads, at the more than one time points, an output value corresponding to a diastolic interval;
- determining a restitution curve for each of the plurality of leads based on the output value corresponding to the action potential and the output value corresponding to the diastolic interval at the more than one time points;
- determining a gradient of the restitution curve for each of the plurality of leads at a first time point;
- combining the gradients determined for each lead;
- or
- identifying the steepest gradient amongst the gradients taken for each lead at the first time point,
- wherein a steeper gradient indicates a higher likelihood to progress to cardiac failure.
An apparatus for assessing the function of the heart, the apparatus comprising:
- an ECG having a plurality of leads;
- and
- a computer in communication with the ECG, wherein the computer performs the steps of:
- determining, for each lead of the plurality of leads, at more than one time point, an output value corresponding to an action potential duration;
- determining, for each lead of the plurality of leads, at the more than one time points, an output value corresponding to a diastolic interval;
- determining a based on the output value corresponding to the action potential and the output value corresponding to the diastolic interval at the more than one time points;
- determining a gradient of the restitution curve for each of the plurality of leads at a first time point;
- combining the gradients determined for each lead;
- or
- identifying the steepest gradient amongst the gradients taken for each lead at the first time point,
- wherein a steeper gradient indicates a higher likelihood to progress to cardiac failure.
One or more non-transitory computer storage media having computer-executable instructions embodied thereon that, when executed, perform a method for assessing the electrical function of a heart, the method comprising:
- communicating with an ECG, the ECG having a plurality of leads;
- receiving, at more than one time point, an output value corresponding to an action potential duration from each lead of the plurality of leads;
- receiving, at the more than one time points, an output value corresponding to a diastolic interval from each lead of the plurality of leads;
- determining a restitution curve based on the output value corresponding to the action potential and the output value corresponding to the diastolic interval, for each lead of the plurality leads at the more than one time points;
- determining a gradient of the restitution curve for each of the plurality of leads at a first time point;
- combining the gradients determined for each lead;
- or
- identifying the steepest gradient amongst the gradients taken for each lead at the first time point,
- wherein a steeper gradient indicates a higher likelihood to progress to cardiac failure.
Dependencies are inferred from the claim text.