US 10,307,050 B2 · Early prediction of hypertensive retinopathy

Abstract

An embodiment of the invention receives by an interface a retinal image from a patient, and identifies by a feature extraction device vessel fragments in the retinal image. The vessel fragments include at least a portion of a major vessel and at least a portion of a branch connected to a major vessel. A processor computes estimated blood flow velocities in the vessel fragments with a blood flow velocity estimation model and determines actual blood flow velocities in the vessel fragments. An analysis engine compares the actual blood flow velocities in the vessel fragments to the estimated blood flow velocities in the vessel fragments. The analysis engine detects a candidate plaque affected vessel fragment when the estimated blood flow velocities in the vessel fragments differs from the actual blood flow velocities in the vessel fragments by a predetermined amount.

Claims13

Dependent claims

A method of early detection of hypertensive retinopathy, said method comprising:

receiving by an interface a retinal image from a patient;
identifying by a feature extraction device vessel fragments in the retinal image, the vessel fragments including at least a portion of a major vessel and at least a portion of a branch connected to a major vessel;
computing, by processing circuitry, estimated blood flow velocities in the vessel fragments with a blood flow velocity estimation model;
determining, via a multi-spectral imaging device and from the retinal image, actual blood flow velocities in the vessel fragments;
comparing, by the processing circuitry, the actual blood flow velocities in the vessel fragments to the estimated blood flow velocities in the vessel fragments;
and
detecting, by the processing circuitry, a candidate plaque affected vessel fragment indicating hypertensive retinopathy when the estimated blood flow velocities in the vessel fragments differs from the actual blood flow velocities in the vessel fragments by a predetermined amount.

4 more elements

A method of early detection of hypertensive retinopathy, said method comprising:

receiving, by an interface, retinal images of individuals in a cohort of individuals known to not have hypertensive retinopathy;
generating, by processing circuitry, a blood flow velocity estimation model from the retinal images of the individuals in the cohort of individuals known to not have hypertensive retinopathy;
receiving, by the interface, a retinal image for a patient;
identifying, by a feature extraction device, vessel fragments in the retinal image, the vessel fragments including at least a portion of a major vessel and at least a portion of a branch connected to a major vessel;
computing, by the processor, estimated blood flow velocities in the vessel fragments as a function of the blood flow velocity estimation model;
determining, via a multi-spectral imaging device and based on the retinal image, actual blood flow velocities in the vessel fragments;
comparing, by an analysis engine, the actual blood flow velocities in the vessel fragments to the estimated blood flow velocities in the vessel fragments;
and
detecting, by the analysis engine, a candidate plaque affected vessel fragment indicating hypertensive retinopathy when the estimated blood flow velocities in the vessel fragments differs from the actual blood flow velocities in the vessel fragments by a predetermined amount.

6 more elements

Dependencies are inferred from the claim text.

Early prediction of hypertensive retinopathy

Life of this patent

Early prediction of hypertensive retinopathy

Life of this patent

Abstract

Claims13