US 10,246,712 B2Granted

Genetic or pharmacological reduction of PERK enhances cortical- and hippocampus-dependent cognitive function

AssigneeCarmel-Haifa University Economic Corp. Ltd.

InventorsKobi Rosenblum, Vijendra Sharma, Hadile Ounallah Saad

Life of this patent

Estimating the term…

Abstract

A method for improving a cognitive function in a subject comprising administering to said subject an active agent reducing PKR-like endoplasmic reticulum kinase (PERK) activity is provided.

Claims17

Dependent claims

A method for improving a cognitive function in a subject having age-related cognitive dysfunction, said method comprising administering to said subject an active agent reducing PKR-like endoplasmic reticulum kinase (PERK) activity.

Dependencies are inferred from the claim text.

Facts

Application: 15/335,466Filed 27 Oct 2016 · us provisional application
Priority: 28 Oct 2015
Published: US 2018/0265873 A120 Sep 2018
Granted: 2 Apr 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

C12N 15/1137
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming…: against enzymes
A61K 9/0085
Galenical forms characterised by the site of application: brain, e.g. brain implants; Spinal cord
A61K 31/519
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim: ortho- or peri-condensed with heterocyclic rings
A61P 25/00
Drugs for disorders of the nervous system

Family

Application62/247,255Us provisional application · filed 28 Oct 2015
US 2018/0265873 A1Pre-grant publication · published 20 Sep 2018
US 10,246,712 B2This patent

From the US filing history. Foreign family members aren’t listed.

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