Medical patch
AssigneesSeoul National University RDB foundation, Industry-Academic Cooperation Foundation, Yonsei University
InventorsHong Koo Baik, Woo Soon Jang, Tae Il Lee, Byung Soo Kim, Suk Ho Bhang, Wan Geun La
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Abstract
A medical patch having an electric potential generating structure which is attachable to a wound to thus regenerate injured skin tissues is provided. The medical patch includes a unit patch having a piezoelectric potential generating structure. The unit patch includes a first layer, a second layer and a piezoelectric nanomaterial disposed between the first and second layers.
Claims21
A medical patch having an electric potential generating structure which is attachable to a wound to thus regenerate injured skin tissues, the medical patch having a piezoelectric potential generating structure comprising a plurality of unit patches stacked one on another, each of the plurality of unit patches comprising a first layer, a second layer and a plurality of piezoelectric nanorods disposed between the first and second layers,
- wherein when the medial patch is attached to a skin for use, the piezoelectric potential generating structure converts mechanical energy originating from a movement of muscle into a piezoelectric potential,
- wherein the plurality of piezoelectric nanorods comprise a plurality of biaxially-grown piezoelectric nanorods, which are aligned horizontally along with in-plane direction of the first layer or the second layer,
- wherein the plurality of biaxially-grown piezoelectric nanorods have an average length ranging from 2.5 μm to 3 μm and an average diameter ranging from 200 nm to 250 nm, and are symmetrically bent based on middle portion of the nanorods by the muscle movement of the skin to which the patch is attached,
- wherein when mechanical load is applied to the biaxially-grown piezoelectric nanorods by the muscle movement of the skin, a first half of each of the biaxially-grown piezoelectric nanorods exhibits positively polarized piezoelectric potentials and a second half opposed to the first half of each of the biaxially-grown piezoelectric nanorods exhibits negatively polarized piezoelectric potentials,
- wherein the first and second layers are flexible such that the medical patch is attachable to the skin for use.
A method of fabricating a medical patch having an electric potential generating structure which is attachable to a wound to thus regenerate injured skin tissues, the method comprising the following steps of:
- (a) preparing powders of piezoelectric nanorods;
- (b) forming a layer of piezoelectric nanorods by dispersing and rubbing the powders of piezoelectric nanorods on a first layer which is coated on a substrate;
- (c) forming a second layer on the layer of piezoelectric nanorods;
- and
- (d) forming a unit patch having a piezoelectric potential generating structure by separating the first layer and the substrate from each other,
- wherein the piezoelectric nanorods comprise a plurality of biaxially-grown piezoelectric nanorods, which are aligned horizontally along with in-plane direction of the first layer or the second layer,
- wherein the plurality of biaxially-grown piezoelectric nanorods have an average length ranging from 2.5 μm to 3 μm and an average diameter ranging from 200 nm to 250 nm,
- wherein when mechanical load is applied to the biaxially-grown piezoelectric nanorods by the muscle movement of the skin, a first half of each of the biaxially-grown piezoelectric nanorods exhibits positively polarized piezoelectric potentials and a second half opposed to the first half of each of the biaxially-grown piezoelectric nanorods exhibits negatively polarized piezoelectric potentials,
- wherein the first and second layers are flexible such that the medical patch is attachable to the skin for use.
A medical patch having an electric potential generating structure which is attachable to a wound to thus regenerate injured skin tissues, the medical patch comprising a unit patch having a piezoelectric potential generating structure, the unit patch comprising a first layer, a second layer and a piezoelectric nanomaterial disposed between the first and second layers, wherein the unit patch generates a piezoelectric potential by a muscle movement of the skin to which the patch is attached, without a separate electric potential generating system,
- wherein the piezoelectric nanomaterial is a plurality of biaxially-grown piezoelectric nanorods, which are aligned horizontally along with in-plane direction of the first layer or the second layer,
- wherein the plurality of biaxially-grown piezoelectric nanorods have an average length ranging from 2.5 μm to 3 μm and an average diameter ranging from 200 nm to 250 nm, and are symmetrically bent based on middle portion of the nanorods by the muscle movement of the skin to which the patch is attached,
- wherein when mechanical load is applied to the biaxially-grown piezoelectric nanorods by the muscle movement of the skin, a first half of each of the biaxially-grown piezoelectric nanorods exhibits positively polarized piezoelectric potentials and a second half opposed to the first half of each of the biaxially-grown piezoelectric nanorods exhibits negatively polarized piezoelectric potentials,
- wherein the first and second layers are flexible such that the medical patch is attachable to the skin for use.
Dependencies are inferred from the claim text.