Polymer-clay composite and organoclay
AssigneeUniversity of Southampton
InventorsRichard Oreffo, Jonathan Dawson, David Gibbs, Jons Hilborn, Dmitri Ossipov
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Abstract
The invention relates to a polymer-clay composite material comprising clay nanoparticles and a polymer, and wherein (a) the polymer comprises phosphate and/or phosphonate ligands; or (b) the polymer-clay composite further comprises linker molecules comprising a phosphate or phosphonate ligand, wherein the linker molecules are arranged to be anchored to the polymer. The invention further relates to organoclays, BMP-clay composite material. Uses, treatments, and manufacturer of the material are also provided.
Claims13
An implantable or injectable bone morphogenic protein (BMP)-clay composite material for the promotion of bone growth in a subject comprising:
- clay nanoparticles;
- and
- BMP, wherein the BMP is provided at a concentration of between 0.5 μg/cm3 and 5 μg/cm3 of the BMP-clay composite material.
Dependencies are inferred from the claim text.