Back to results
US 10,245,313 B2Granted
DNA motif compounds and methods for inducing specific antibodies and cellular immunity
AssigneesVersitech Limited, Nanjing University
InventorsZhiwei Chen, Xilin Wu, Zhiwei Wu
Life of this patent
Estimating the term…
Abstract
The present invention relates to the field of applied immunotechnology and medicine. More specifically, it relates to DNA motif vaccine design, glyco-DNA motif vaccine design, and immunogen design for producing antibodies against an epitope of arbitrary sequences or polysaccharide epitope, particularly those epitopes against which it is otherwise very difficult to induce antibodies, such as those of HIV-1. The present invention also relates to immunogen design to induce robust cellular and humoral immunity.
Claims9
An immunogenic composition comprising:
- a mixture of different plasmids, each of which encodes a motif peptide comprising the sequence xxxxxNCSFNITTxxxx (SEQ ID NO:
- 1), wherein x stands for any amino acid residue, and wherein the x residues flanking NCSFNITT motif are different when compared to another plasmid in the mixture.
Dependencies are inferred from the claim text.