Probiotic strains for use in treatment or prevention of osteoporosis
AssigneeProbi AB
InventorsAnna Berggren, Niklas Larsson, Gunilla Önning, Irini Lazou Ahrén, Klara Sjögren, Claes Ohlsson
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Abstract
The present invention relates to at least one probiotic strain chosen from Lactobacillus paracasei, or at least one probiotic strain chosen from Lactobacillus paracaseiin combination with at least one probiotic strain chosen from Lactobacillus plantarum, for use in the treatment or prevention of osteoporosis or for use in increasing the absorption of at Ca2+ ions, in a mammal, preferably in a human.
Claims30
A method for treating or inhibiting osteoporosis, treating or inhibiting bone loss, or increasing the absorption of Ca2+ ions, comprising orally administering to a mammal a composition comprising a therapeutically effective amount of at least one probiotic strain selected from the group consisting of Lactobacillus paracasei 8700:2, DSM 13434, and Lactobacillus paracasei 02:A, DSM 13432, wherein the composition is supplemented with additional Ca2+ in the form of a salt, wherein the inhibition of osteoporosis or bone loss is by reducing osteoporosis or bone loss compared to osteoporosis or bone loss without administration of said composition, and wherein increasing the absorption of Ca2+ ions is compared to absorption of Ca2+ ions without administration of said composition.
A method for treating or inhibiting osteoporosis, treating or inhibiting bone loss, or increasing the absorption of Ca2+ ions, in a woman, comprising orally administering to a woman a therapeutically effective amount of at least one probiotic strain selected from the group consisting of Lactobacillus paracasei 8700:2, DSM 13434, and Lactobacillus paracasei 02:A, DSM 13432, wherein the inhibition of osteoporosis or bone loss is by reducing osteoporosis or bone loss compared to osteoporosis or bone loss without administration of said at least one probiotic strain, and wherein increasing the absorption of Ca2+ ions is compared to absorption of Ca2+ ions without administration of said composition.
Dependencies are inferred from the claim text.