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US 10,245,273 B2Granted
Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents
AssigneeClarus Therapeutics, Inc.
InventorsWael Salameh, Panayiotis Constantinides
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Abstract
Pharmaceutical products comprising a hypolipidemic agent and a testosterone ester such as testosterone undecanoate are provided. Methods of safely treating a testosterone deficiency or its symptoms with the inventive pharmaceutical products are also provided.
Claims11
A oral pharmaceutical composition comprising:
- a. a hypolipidemic agent that is a peroxisome proliferator activating receptor (PPAR) agonist;
- and
- b. 18 to 22 percent by weight of solubilized testosterone undecanoate, solubilized in a carrier comprising
- i. 15 to 17 percent by weight of hydrophilic surfactant;
- ii. 50 to 55 percent by weight of lipophilic surfactant;
- and
- iii. 10-15 percent by weight of a mixture of borage oil and peppermint oil.
4 more elements
Dependencies are inferred from the claim text.