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US 10,245,270 B2Granted
Salt of 3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione, its preparation, and formulations containing it
AssigneeLes Laboratoires Servier
InventorsAlexandre Le Flohic, Jérôme Guidotti, Philippe Letellier
Life of this patent
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Abstract
3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione methanesulphonate of formula (II): Medicinal products containing the same which are useful in treating cancer.
Claims8
E isomer of 3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione methanesulphonate of formula (II):
- having an X-ray powder diffractogram which exhibits the Bragg's angles 2 theta (expressed in terms of °+0.2) 7.55;
- 10.42;
- 14.84;
- 15.06;
- 15.25;
- 15.80;
- 16.81;
- 17.01;
- 17.95;
- 19.06;
- 20.00;
- 20.29;
- 21.88;
- 23.87;
- 24.31;
- 24.64;
- 26.13;
- 26.59.
15 more elements
Dependencies are inferred from the claim text.