Substituted imidazo[1,2-a]pyrazines as soluble guanylate cyclase activators
AssigneeMerck Sharp & Dohme Corp.
InventorsJoie Garfunkle, Olga Ornoski, Dann L. Parker, Jr., Subharekha Raghavan, Libo Xu
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AssigneeMerck Sharp & Dohme Corp.
InventorsJoie Garfunkle, Olga Ornoski, Dann L. Parker, Jr., Subharekha Raghavan, Libo Xu
Estimating the term…
A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or pharmaceutically acceptable salt thereofs, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of Formula I or pharmaceutically acceptable salts thereof.
A compound having structural Formula I:
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.