Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis or treatment of sensitive skin

A method for the treatment or prophylaxis of sensitive skin, itching, dry skin, as well as of inflammatory states of the human skin, wherein the method comprises applying to skin of a subject in need thereof a cosmetic or dermatological preparation comprising one or more alkylamidothiazoles of the following formula in an amount which is effective for the treatment or prophylaxis of sensitive skin, itching, dry skin, inflammatory states of the human skin:

• in which
• R1, R2, X and Y are different, partly identical or completely identical and, independently of one another, represent:
• R1=—C1-C24-alkyl (linear and branched), —C1-C24-alkenyl (linear and branched), —C1-C8-cycloalkyl, —C1-C8-cycloalkyl-alkylhydroxy, —C1-C24-alkylhydroxy (linear and branched), —C1-C24 alkylamine (linear and branched), —C1-C24-alkylaryl (linear and branched), —C1-C24-alkylaryl-alkyl-hydroxy (linear and branched), —C1-C24-alkylheteroaryl (linear and branched), —C1-C24-alkyl-O—C1-C24-alkyl (linear and branched), —C1-C24 alkyl-morpholino, —C1-C4 alkyl-piperidino, —C1-C24 alkyl-piperazino, or —C1-C24 alkyl-piperazino-N-alkyl;
• R2=H, —C1-C24-alkyl (linear and branched), —C1-C24-alkenyl (linear and branched), —C1-C8-cycloalkyl, —C1-C24-hydroxyalkyl (linear and branched), —C1-C24-alkylaryl (linear and branched), or —C1-C24-alkylheteroaryl (linear and branched);
• X=-phenyl, optionally mono- or polysubstituted with —OH, —F, —Cl, —Br, —I, —OMe, —NH2, —CN, or cetyl;
• Y=H, —C1-C24-alkyl (linear and branched), —C1-C24-alkenyl (linear and branched), —C1-C8-cycloalkyl, —C1-C24-aryl, —C1-C24-heteroaryl, —C1-C24-alkylaryl (linear and branched), —C1-C24-alkylheteroaryl (linear and branched), -phenyl, -2,4-dihydroxyphenyl, -2,3-dihydroxyphenyl, -2,4-dimethoxyphenyl, -2,3-dimethoxyphenyl, —COO-alkyl, —COO— alkenyl, —COO-cycloalkyl, —COO-aryl, or —COO-heteroaryl;
• and wherein the one or more alkylamidothiazoles are present as a free base and/or as a cosmetically and dermatologically acceptable salt thereof.