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US 10,245,137 B2Granted
Graft with expandable region and methods of making and using the same
AssigneeAtrium Medical Corporation
InventorsJames J. Scutti, David G. Culp, Ibrahim E. Dagher, Kevin W. Penn
Life of this patent
Estimating the term…
Abstract
A vascular graft suitable for implantation, and more particular to a vascular graft having an expandable outflow region for restoring patency of the graft after implantation into a body lumen.
Claims17
A graft, comprising:
- a conduit having a wall, the conduit comprising:
- a body region;
- an outflow region located adjacent to the body region;
- at least one inflow aperture at an inflow end of the body region;
- and
- an outflow aperture at an outflow end of the outflow region opposite from the at least one inflow aperture;
- wherein the wall comprises a support structure and a biocompatible layer;
- and wherein the support structure along the outflow region configurable from a first shape to a second shape, the second shape being a flared shape having an expanded diameter along at least a portion of its length, and the first shape having a constrained diameter, smaller than the expanded diameter, along the outflow region due to the support structure along the outflow region being under continuous compressive stress resulting from a continuous applied load caused by the biocompatible layer against the support structure, wherein the compressive stress resulting from the continuous applied load in the outflow region is greater than a compressive stress resulting from a continuous applied load in the body region;
- and
- wherein the support structure assumes the flared shape prior to combination with the biocompatible layer to form the wall, and the flared shape has multiple effective outer diameter measurements, and the support structure assumes the first shape after combination with the biocompatible layer to form the wall, and the first shape has a generally uniform effective outer diameter measurement.
7 more elements
A vascular graft, comprising:
- a conduit having a wall, the conduit comprising:
- a body region;
- an outflow region located adjacent to the body region;
- at least one inflow aperture at an inflow end of the body region;
- and
- an outflow aperture at an outflow end of the outflow region opposite from the at least one inflow aperture;
- wherein the wall comprises a support structure and a biocompatible layer;
- wherein prior to combination with the biocompatible layer to form the wall, the support structure comprises multiple effective outer diameter measurements along its length comprising a constant effective outer diameter measurement along the body region, and a flared shape along the outflow region defined by an effective outer diameter measurement along the outflow region that is incrementally greater at each segment along the support structure that is incrementally more distal from the at least one inflow aperture;
- wherein after combination with the biocompatible layer to form the wall, the support structure in the outflow region is under continuous compressive stress resulting from a continuous applied load caused by the biocompatible layer which maintains the support structure along the outflow region at a constrained effective outer diameter measurement that is not incrementally greater at each segment along the support structure that is incrementally more distal from the at least one inflow aperture, wherein the compressive stress resulting from the continuous applied load in the outflow region is greater than a compressive stress resulting from a continuous applied load in the body region;
- and
- wherein after application of a counter force to the support structure in the outflow region the support structure in the outflow region is reconfigured from the constrained effective outer diameter measurement to an expanded effective outer diameter measurement, at least a portion of which is at least one millimeter greater than the constrained effective outer diameter measurement.
8 more elements
A graft, comprising:
- a conduit having a wall, the conduit comprising:
- a body region;
- an outflow region located adjacent to the body region;
- at least one inflow aperture at an inflow end of the body region;
- and
- an outflow aperture at an outflow end of the outflow region opposite from the at least one inflow aperture;
- wherein the wall comprises a support structure and a biocompatible layer;
- and wherein the support structure along the outflow region configurable from a first shape to a second shape, the second shape being a flared shape having an expanded diameter along at least a portion of its length, and the first shape having a constrained diameter, smaller than the expanded diameter, along the outflow region due to the support structure along the outflow region being under continuous compressive stress resulting from a continuous applied load caused by the biocompatible layer against the support structure, wherein the compressive stress resulting from the continuous applied load in the outflow region is greater than a compressive stress resulting from a continuous applied load in the body region;
- wherein the support structure assumes the flared shape prior to combination with the biocompatible layer to form the wall, and the flared shape has multiple effective outer diameter measurements, and the support structure assumes the first shape after combination with the biocompatible layer to form the wall, and the first shape has a generally uniform effective outer diameter measurement;
- and
- wherein the multiple effective outer diameter measurements along the outflow region comprise an effective outer diameter measurement that is incrementally greater at each segment along the support structure that is incrementally more distal from the at least one inflow aperture.
8 more elements
Dependencies are inferred from the claim text.