Closure device and methods for making and using them

A method comprising:

• locating an opening in tissue;
• and
• following locating the opening, deploying a medical device near the opening so that a portion of the medical device engages tissue, the medical device comprising:
• a plurality of members forming a body, the body being configured to transition from a delivery configuration to a deployed configuration, the plurality of members forming a plurality of openings with a long axis extending substantially longitudinally relative to a longitudinal axis of the medical device in the delivery configuration, wherein each opening has a mid-portion having a width in a direction transverse to the long axis of the opening greater than widths of a remainder of the opening in the deployed configuration;
• and
• a plurality of end portions disposed at a distal portion of the medical device, each end portion extending towards the longitudinal axis in the deployed configuration.