Back to results
US 10,221,252 B2Granted
Chondroitin sulphate purification method
AssigneeAltergon S.A.
InventorsMario De Rosa, Chiara Schiraldi
Life of this patent
Estimating the term…
Abstract
The present invention relates to a downstream industrial method of purifying chondroitin sulphate obtained from animal cartilage, which produces a product fully compliant with the specifications required for the use of said compound in the pharmaceutical field.
Claims7
A method for the separation of chondroitin sulphate (CS) and keratan sulphate (KS) from an aqueous solution containing them, comprising adding to the aqueous solution a water-miscible organic solvent under conditions of ionic strength, which induces formation of two liquid phases with an interface in-between:
- a dense phase in which CS concentrates, said dense phase primarily comprising said water-miscible organic solvent and a light phase in which KS concentrates, said light phase primarily comprising water, wherein said water-miscible organic solvents are selected from the group consisting of 2-propanol, 1-propanol, 2-propanol/2-butanol, ethanol and acetone.
Dependencies are inferred from the claim text.