Self-contained diagnostic test with advanceable test strip

A self-contained device for determining the presence of an analyte, the device comprising:

• a testing chamber comprising an open portion at or near a first end, a reagent mixing portion at or near a second end opposite the first end, and a wall extending from the open portion to the reagent mixing portion;
• an articulable element coupled to the testing chamber, wherein the articulable element can be articulated to cause a plurality of reagents held by the testing chamber to mix in the reagent mixing portion;
• a cover operably coupled to the open portion of the testing chamber and configured to allow advancement of a specimen into the reagent mixing portion of the testing chamber and close off the open portion;
• and
• a movable test strip located outside the wall of the testing chamber and configured to be actuated by a mechanism coupled to the testing chamber and the movable test strip, wherein actuation by the mechanism is configured to cause the movable test strip to be advanced outside the wall of the testing chamber into the reagent mixing portion of the testing chamber to determine the presence of an analyte in a mixture of the plurality of reagents and the specimen, wherein the determination comprises a visual change on the movable test strip that is read in the self-contained device.